Gene information
Official symbol TNFRSF11B
Official full name TNF receptor superfamily member 11b
Gene type protein-coding gene
Chromosome8q24.12
Alias symbolOCIF; TR1
Previous symbolOPG
Gene familyTumor necrosis factor receptor superfamily
Resources
Entrez Gene 4982
HGNC HGNC:11909
Ensembl ENSG00000164761
Vega OTTHUMG00000164969
UCSC uc003yon.5
GO terms: 37 records
GO Description Category LogP Number of genes Detail
GO:0001501 skeletal system development GO Biological Processes -17.2073293 69 More
GO:0002683 negative regulation of immune system process GO Biological Processes -26.6415063 77 More
GO:0002761 regulation of myeloid leukocyte differentiation GO Biological Processes -12.4818724 17 More
GO:0002762 negative regulation of myeloid leukocyte differentiation GO Biological Processes -4.32673439 6 More
GO:0005125 cytokine activity GO Molecular Functions -54.7097150 57 More
GO:0007584 response to nutrient GO Biological Processes -29.4823239 48 More
GO:0009410 response to xenobiotic stimulus GO Biological Processes -32.6021211 82 More
GO:0009725 response to hormone GO Biological Processes -49.1091700 138 More
GO:0009991 response to extracellular stimulus GO Biological Processes -42.2178323 102 More
GO:0010035 response to inorganic substance GO Biological Processes -29.1720710 89 More
GO:0010038 response to metal ion GO Biological Processes -20.5090881 61 More
GO:0030198 extracellular matrix organization GO Biological Processes -21.4880730 33 More
GO:0030312 external encapsulating structure GO Cellular Components -73.3689453 93 More
GO:0030545 signaling receptor regulator activity GO Molecular Functions -87.4728446 102 More
GO:0030546 signaling receptor activator activity GO Molecular Functions -90.4065983 101 More
GO:0031012 extracellular matrix GO Cellular Components -73.4416071 93 More
GO:0031667 response to nutrient levels GO Biological Processes -41.8130555 98 More
GO:0032026 response to magnesium ion GO Biological Processes -3.03478521 5 More
GO:0034103 regulation of tissue remodeling GO Biological Processes -21.5631413 32 More
GO:0034104 negative regulation of tissue remodeling GO Biological Processes -6.91942497 9 More
GO:0043062 extracellular structure organization GO Biological Processes -21.4370160 33 More
GO:0043627 response to estrogen GO Biological Processes -7.69647850 16 More
GO:0045124 regulation of bone resorption GO Biological Processes -6.02130395 7 More
GO:0045229 external encapsulating structure organization GO Biological Processes -21.3355594 33 More
GO:0045596 negative regulation of cell differentiation GO Biological Processes -26.9785067 101 More
GO:0045637 regulation of myeloid cell differentiation GO Biological Processes -9.39364926 18 More
GO:0045638 negative regulation of myeloid cell differentiation GO Biological Processes -3.67865682 7 More
GO:0045670 regulation of osteoclast differentiation GO Biological Processes -10.2566667 12 More
GO:0045779 negative regulation of bone resorption GO Biological Processes -4.33413085 4 More
GO:0046850 regulation of bone remodeling GO Biological Processes -7.11509809 13 More
GO:0046851 negative regulation of bone remodeling GO Biological Processes -4.18483678 6 More
GO:0048018 receptor ligand activity GO Molecular Functions -91.0736151 101 More
GO:1902105 regulation of leukocyte differentiation GO Biological Processes -18.8286876 32 More
GO:1902106 negative regulation of leukocyte differentiation GO Biological Processes -7.27922558 19 More
GO:1903706 regulation of hemopoiesis GO Biological Processes -16.2759166 33 More
GO:1903707 negative regulation of hemopoiesis GO Biological Processes -7.72888419 20 More
GO:2000027 regulation of animal organ morphogenesis GO Biological Processes -7.86416421 22 More
KEGG pathways: 2 records
KEGG Description Category LogP Number of genes Detail
hsa04060 Cytokine-cytokine receptor interaction KEGG Pathway -61.0014447 66 More
hsa04380 Osteoclast differentiation KEGG Pathway -7.05199617 21 More
Drug-Gene interaction
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Related drugs: 5 records
Related studies: 22 records
Molecular factor Omics type Application Objective MI type Reference
TNFRSF11B transcriptomics medium predictor left ventricular dysfunction[prognosis (bad)] acute ST elevation myocardial infarction Lindberg S et al. Can J Cardiol. 2014
tumor necrosis factor receptor superfamily member 11B proteomics adverse events[prognosis (bad)] acute myocardial infarction Ueland T et al. J Am Coll Cardiol. 2004
tumor necrosis factor receptor superfamily member 11B proteomics adverse events[prognosis (bad)] acute myocardial infarction Ueland T et al. J Am Coll Cardiol. 2004
tumor necrosis factor receptor superfamily member 11B proteomics adverse events[prognosis (bad)] acute myocardial infarction Ueland T et al. J Am Coll Cardiol. 2004
tumor necrosis factor receptor superfamily member 11B proteomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Crisafulli A et al. Clin Sci (Lond). 2005
tumor necrosis factor receptor superfamily member 11B proteomics poor predictor acute type 5 myocardial infarction[diagnosis] acute type 5 myocardial infarction Hermann-Arnhof KM et al. Crit Care Med. 2006
tumor necrosis factor receptor superfamily member 11B proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Halapas A et al. Clin Chem Lab Med. 2008
tumor necrosis factor receptor superfamily member 11B proteomics increased myocardial infarct size[prognosis (bad)] acute ST elevation myocardial infarction Andersen GO et al. Heart. 2011
tumor necrosis factor receptor superfamily member 11B proteomics poor predictor left ventricular remodeling[prognosis (bad)] acute ST elevation myocardial infarction Erkol A et al. Atherosclerosis. 2012
tumor necrosis factor receptor superfamily member 11B proteomics no-reflow phenomenon[prognosis (bad)] acute ST elevation myocardial infarction Erkol A et al. Atherosclerosis. 2012
tumor necrosis factor receptor superfamily member 11B proteomics no-reflow phenomenon[prognosis (bad)] acute ST elevation myocardial infarction Fuernau G et al. Int J Cardiol. 2013
tumor necrosis factor receptor superfamily member 11B proteomics major adverse cardiovascular events[prognosis (bad)] acute ST elevation myocardial infarction Fuernau G et al. Int J Cardiol. 2013
tumor necrosis factor receptor superfamily member 11B proteomics major adverse cardiovascular events[prognosis (bad)] acute ST elevation myocardial infarction Fuernau G et al. Int J Cardiol. 2013
tumor necrosis factor receptor superfamily member 11B proteomics major adverse cardiovascular events[prognosis (bad)] acute ST elevation myocardial infarction Canga A et al. J Cardiol. 2012
tumor necrosis factor receptor superfamily member 11B proteomics recurrent myocardial infarction[prognosis (bad)] acute ST elevation myocardial infarction Pedersen S et al. Cardiology. 2012
tumor necrosis factor receptor superfamily member 11B proteomics death[prognosis (bad)] acute ST elevation myocardial infarction Pedersen S et al. Cardiology. 2012
tumor necrosis factor receptor superfamily member 11B proteomics heart failure[prognosis (bad)] acute ST elevation myocardial infarction Pedersen S et al. Cardiology. 2012
tumor necrosis factor receptor superfamily member 11B proteomics death;heart failure;recurrent myocardial infarction[prognosis (bad)] acute ST elevation myocardial infarction Pedersen S et al. Cardiology. 2012
tumor necrosis factor receptor superfamily member 11B proteomics death[prognosis (bad)] acute ST elevation myocardial infarction Bjerre M et al. Eur J Prev Cardiol. 2013
tumor necrosis factor receptor superfamily member 11B proteomics adverse events[prognosis (bad)] acute ST elevation myocardial infarction Bjerre M et al. Eur J Prev Cardiol. 2013
tumor necrosis factor receptor superfamily member 11B proteomics microvascular dysfunction[prognosis (bad)] acute myocardial infarction Logstrup BB et al. Coron Artery Dis. 2013
tumor necrosis factor receptor superfamily member 11B proteomics death[prognosis (bad)] acute myocardial infarction Fuernau G et al. Eur J Heart Fail. 2014
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